HIGHLIGHTS
- who: Ece Ergir from the Center for TranslationalUniversity Hospital Ricerca Scientifica, Rome, Italy have published the research: Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture, in the Journal: Scientific Reports Scientific Reports
- what: Given that long-term cultured 3D cardiac microtissues possess the abovementioned characteristics, the authors propose that the hOCMTs can be defined as human cardiac organoids (hCOs).
- how: Throughout the study the authors used 2D monolayer cultures as controls.
SUMMARY
2D‑to‑3D culture switch promotes spontaneous cardiac microtissue formation . . .
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