Generation of myocyte agonal ca2+ waves and contraction bands in perfused rat hearts following irreversible membrane permeabilisation

HIGHLIGHTS

  • who: Yuma Morishita from the DepartmentKyoto Prefectural University of have published the research work: Generation of myocyte agonal Ca2+ waves and contraction bands in perfused rat hearts following irreversible membrane permeabilisation, in the Journal: Scientific Reports Scientific Reports
  • what: This study shows the high-frequency u00adCa2+ waves and coexisting contraction bands within the myocytes of perfused rat hearts following saponin-permeabilised membrane injury.

SUMMARY

    In the absence of saponin, individual myocytes exhibited spatiotemporally uniform C ­ a2+ transients during systole and no abnormal increasesi concentration during diastole as shown in the sequential . . .

     

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