Generation of transcript length variants and reprogramming of mrna splicing during atherosclerosis progression in apoe-deficient mice

HIGHLIGHTS

• What: The authors report the lengthening of the 5′ UTR/3′ UTRs and the shortening of the CDS in downregulated mRNAs during ATS progression. Lastly, the authors aimed the mechanisms causing length variations among the transcript variants described above. The original microarray expression data idenshowing that thefrom relationship miRNA/mRNA is much more complex than previously tified mRNAs upor downregulated in the experimental conditions , and here the authors report the results of the analysis of the downregulated transcripts. In this context, the authors aimed to study the variability in the 3 UTRs of put that included the . . .
  

   

  

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