Generation of transgenic sperm expressing gfp by lentivirus transduction of spermatogonial stem cells in vivo in cynomolgus monkeys

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  • who: Shengnan Wang et al. from the State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China have published the article: Generation of Transgenic Sperm Expressing GFP by Lentivirus Transduction of Spermatogonial Stem Cells In Vivo in Cynomolgus Monkeys, in the Journal: (JOURNAL)
  • what: The aim of this study was to create genetically modified primate SSCs via lentiviral transduction. The authors injected EGFP lentiviruses into testicular reticulum of cynomolgus macaques and successfully obtained transgenic sperm. The preliminary data from the experiments showed that EGFP transgenes . . .

     

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