Genes expressed at low levels raise false discovery rates in rna samples contaminated with genomic dna

HIGHLIGHTS

  • who: Xiangnan Li from the (UNIVERSITY) have published the article: Genes expressed at low levels raise false discovery rates in RNA samples contaminated with genomic DNA, in the Journal: (JOURNAL)
  • what: The authors show that low-abundance transcripts account for inaccuracies in RNA-seq data. The authors show here that contamination with gDNA altered the quantitation of low-abundance transcripts, which generated false results. These findings will serve as a valuable resource to determine the effects of gDNA contamination in studies aimed to discover novel genetic elements. The authors show (Fig 4b) that with 10 . . .

     

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