Genetic and biochemical characterization of human ap endonuclease 1 mutants deficient in nucleotide incision repair activity

HIGHLIGHTS

• who: Repair Activity et al. from the Institut de Cancérologie Gustave Roussy, Villejuif, France, Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of SciencesEditor: Martin GMarinus, University of Massachusetts Medical School, United States of America have published the Article: Genetic and Biochemical Characterization of Human AP Endonuclease 1 Mutants Deficient in Nucleotide Incision Repair Activity, in the Journal: (JOURNAL) of August/17,/2010
• what: The authors investigated the physiological role of NIR function of human AP endonuclease through site-directed_mutagenesis and comparison of mutant APE1 activities in the BER . . .
  

   

  

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