Genetic and molecular mechanisms of hypertrophic cardiomyopathy

HIGHLIGHTS

  • who: Chun Chou and Michael Thomas Chin from the (UNIVERSITY) have published the article: Genetic and Molecular Mechanisms of Hypertrophic Cardiomyopathy, in the Journal: (JOURNAL) of 23/Dec/2022
  • what: The review discussed how alterations in calcium handling, autophagy and cellular metabolism contribute to cellular hypertrophy in a cardiomyocyte-intrinsic manner. The study showed that the plasma_proteins involved in VEGF signaling and pro-inflammatory responses were reduced after myectomy, consistent with prior studies implicating the role of angiogenesis and inflammation in HCM pathogenesis.
  • how: The authors discuss in detail how these techniques can . . .

     

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