HIGHLIGHTS
- who: Elham Masoumi from the Department of Medical Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran have published the Article: Genetic and pharmacological targeting of A2a receptor improves function of anti-mesothelin CAR T cells, in the Journal: (JOURNAL)
- what: In this study the expression of A2aR and the effects of its activation on the function of fully human CAR T cells (MSLN-CAR T) were analyzed. The experiments showed significant A2aR upregulation on T cells during the CAR T cell production procedure (cell activation and transduction). The authors designed a fully . . .
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