Genetic characterization of a unique neuroendocrine transdifferentiation prostate circulating tumor cell-derived explant model

HIGHLIGHTS

• who: Vincent Faugeroux from the CNRS UMS3655-INSERM , AMMICA, Villejuif, France, XenTech, Evry, France. University of have published the paper: Genetic characterization of a unique neuroendocrine transdifferentiation prostate circulating tumor cell-derived eXplant model, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors report the first prostate CDX and show that this model harbored phenotypical and genetic characteristics of CRPC-NE. The authors focused on 250 functional genes that are relevant for CRPC-NE progression and significantly deregulated (CPM ≥2 in at least three samples)7,28. The authors report the use of DLA . . .
  

   

  

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