Genetic control of variegated kir gene expression: polymorphisms of the bi-directional kir3dl1 promoter are associated with distinct frequencies of gene expression

HIGHLIGHTS

• who: Expression and collaborators from the Laboratory of Experimental Immunology, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, Maryland, United States of America have published the research: Genetic Control of Variegated KIR Gene Expression: Polymorphisms of the Bi-Directional KIR3DL1 Promoter Are Associated with Distinct Frequencies of Gene Expression, in the Journal: (JOURNAL) of November/14,/2008
• what: The authors demonstrate for the first time that promoter polymorphisms affecting the strength of competing sense and antisense promoters largely explain the differential frequency of of KIR3DL1 allotypes on NK cells. The authors propose that the . . .
  

   

  

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