Genetic deconvolution of fetal and maternal cell-free dna in maternal plasma enables next-generation non-invasive prenatal screening

HIGHLIGHTS

• who: Chenming Xu from the A total of , samples from human subjects were included in the clinical validation studyThis study was approved by the institutional review boards of China International Peace Maternity and Child Health Hospital (GKLW2019-52) and Obstetrics and Gynecology Hospital of Fudan University (2020-178). Informed consent was obtained from all study participants. This study collected leftover samples from subjects who underwent amniocentesis or chorionic villus sampling for standard prenatal diagnosis. Maternal plasma was collected before their invasive prenatal diagnosis procedures. The results from karyotyping, microarray-based comparative genomic hybridization, and/or sequencing data . . .
  

   

  

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