Genetic determinants of syndactyly: perspectives on pathogenesis and diagnosis

HIGHLIGHTS

  • who: Afraah Cassim from the (UNIVERSITY) have published the research work: Genetic determinants of syndactyly: perspectives on pathogenesis and diagnosis, in the Journal: (JOURNAL)
  • what: Through this article, the authors attempt to better understand the developmental process underlying this condition and the genes involved. The authors propose that a conglomeration of genes in the canonical and noncanonical WNT signaling, Notch signaling, ADAMTS metalloprotease pathways and non-coding regions may work in concert to establish normal development of the limb bud.
  • how: This review discusses the interactions repressing ICD in and characterizes genes associated . . .

     

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