Genetic diversity of candidate loci linked to mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid

HIGHLIGHTS

  • who: Paula J. Gómez-González from the DepartmentUniversidade have published the research work: Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid, in the Journal: Scientific Reports Scientific Reports
  • what: The analysis has identified phylogenetically related mutations that are unlikely to be drug resistance associated, including in large clades mostly encompassing sensitive profiles to first- and second-line drugs, as well as several mutations that were not considered strain-specific (e_g, fbiA G264R, fbiB L558R or fbiC E224G).

SUMMARY

    Co-occurrence of multiple . . .

     

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