Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases

HIGHLIGHTS

• who: Adrien Georges from the Patients and control populationsThe meta-analysis included participants of European ancestry from six studies: ARCADIA8/ , GWAS, Mayo Vascular Disease Biorepository52, DEFINE-FMD study16, ARCADIA-POL53/WOBASZ , study, University of Michigan/Cleveland Clinic Foundation (UM/CCF) study31, and FEIRI7/, study. FMD patients presented similar clinical characteristics (Supplementary Table, ) and homogeneous diagnosis, exclusion and inclusion criteria. Detailed description of the participating cohorts is given below. ARCADIA. FMD patients were included from the ARCADIA (Assessment of Renal and Cervical Artery DysplasIA) register, a national FMD registry at the Georges Pompidou European Hospital, APHP, Paris8. The . . .
  

   

  

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