HIGHLIGHTS
- who: Hiroki Ohara and Toru Nabika from the Department of Functional Pathology, Faculty of Medicine, Shimane University, Izumo, Japan have published the research work: Genetic Modifications to Alter Blood Pressure Level, in the Journal: Biomedicines 2022, 10, 1855. of /2022/
SUMMARY
Hypertension is the leading preventable risk factor for cerebro-cardiovascular complications, including heart failure and stroke. Given that spontaneous cerebro-cardiovascular disease models, such as Dahl salt-sensitive (SS) and stroke-prone spontaneously hypertensive rats (SHRSP), have been commercially available, a genome-editing strategy using the rat disease models has much potential . . .
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