HIGHLIGHTS
- who: Mattia Quattrocelli and colleagues from the Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois have published the paper: Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury, in the Journal: (JOURNAL) of May/31,/2017
- how: The authors hypothesized a feed-forward model in which OPN sustains TGFβ signaling in muscle and its downstream transcriptional factors Slug and Snail which bind E-box DNA elements of target genes (Fig 5A) .
SUMMARY
October 24, 2017 Genetic ablation of osteopontin modifies sarcolemmal injury of . . .
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