Genetic mutations linked to parkinson’s disease differentially control nucleolar activity in pre-symptomatic mouse models

HIGHLIGHTS

  • who: Valentin Evsyukov et al. from the Institute of Anatomy and Medical Cell Biology, University of Heidelberg, Neurology, Goethe University Medical School, Frankfurt am Main, Germany have published the article: Genetic mutations linked to Parkinson's disease differentially control nucleolar activity in pre-symptomatic mouse models, in the Journal: (JOURNAL) of 28/03/2017
  • what: The authors focused on DJ-1/PINK1 DKO mice and control littermates. The study shows a differential effect of PDrelated (PARK) genetic mutations on nucleolar activity. For the experiments reported here, male and female mice were used.
  • how . . .

     

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