Genetic polymorphism, constitutive expression and tissue localization of dirofilaria immitis p-glycoprotein 11: a putative marker of macrocyclic lactone resistance

HIGHLIGHTS

  • who: Emily Curry from the Conclusions: Our data confirm that genetic polymorphism of DimPgp, is associated with ML resistance in USA have published the research: Genetic polymorphism, constitutive expression and tissue localization of Dirofilaria immitis P-glycoprotein 11: a putative marker of macrocyclic lactone resistance, in the Journal: (JOURNAL)
  • what: The authors report an extensive study on the expression of DimPgp-11 and its localization in D. immitis microfilaria (mf ).
  • how: The authors examined the clinically validated D. 11 (DimPgp-11) single nucleotide (SNP) via analysis in three ML-susceptible isolates (Missouri MP3 . . .

     

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