HIGHLIGHTS
- who: Goutham Atla from the Centre for Genomic Regulation, Barcelona, Spain have published the research work: Genetic regulation of RNA splicing in human pancreatic islets, in the Journal: (JOURNAL)
- what: The authors examine splicing QTLs (sQTLs) in pancreatic islets from 399 human donors and observe that common genetic variation has a widespread influence on the splicu2011 ing of genes with established roles in islet and diabetes. Because TWAS findings do not necessarily distinguish between shared genetic effects and linkage , the authors focused on TWAS signals showing colocalization with the GWAS phenotype (PP4 u2265 0.6 . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.