Genetic regulation of serum iga levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits

HIGHLIGHTS

• who: Lili Liu from the genetic determinants of serum IgA levels in individuals from either European or East Asian ancestry, and nine significant GWAS loci have been identified to date16, Notably, African and other more diverse populations have not been included in prior studies, and limited data exist on the ancestral differences in IgA levels. In this study, we conducted a genetic analysis of serum IgA levels in, individuals, including, diverse participants across , ancestry-defined cohorts with genome-wide imputed data combined with, individuals with summary statistics data on significant and suggestive association signals (P andlt have . . .
  

   

  

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