Genetic tagging of the adenosine a2a receptor reveals its heterogeneous expression in brain regions

HIGHLIGHTS

• who: Muran Wang1† and collaborators from the University of Tsukuba, Japan have published the research: Genetic tagging of the adenosine A2A receptor reveals its heterogeneous expression in brain regions, in the Journal: (JOURNAL)
• how: In this study CRISPR/Cas9 technology was employed to modify the mouse Adora2a gene. These results indicated that the genomic modification did not affect A2A R transcription.
• future: Investigations are required to exclude the possibility of abnormal signaling transduction in the A2A R-tag mice. The findings showed that the A2A R-tag is expressed at similar levels and . . .
  

   

  

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