HIGHLIGHTS
- who: Jin Ma from the Chongqing Medical University, China have published the article: Genetic variant rs11136000 upregulates clusterin expression and reduces Alzheimer's disease risk, in the Journal: (JOURNAL)
- what: The authors integrated multiple omics data, including genome-wide association study (GWAS), expression quantitative trait loci (eQTLs), transcriptome and proteome data, to investigate whether rs11136000 regulates CLU expression and thereby contribute to AD. This research has been conducted using the UK Biobank resource.
- how: The authors obtained two GWAS datasets for AD patients with clinical or autopsy diagnosis from International Genomics of Alzheimer . . .
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