HIGHLIGHTS
- who: William Tapper from the Faculty of Medicine, University of Southampton, Southampton , YD, Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury , BJ, UK. , CeMM have published the research: Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 20/02/2015
- what: The authors demonstrate that the 2 candidate risk allele at rs9376092 is associated with reduced MYB expression in normal myeloid cells. This analysis determined that the effects of rs12339666 and rs9376092 were significantly lower in cases without CALR and/or MPL mutations . . .
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