Genetically engineered hepatitis c virus-like particles (hcv-lps) tagged with sp94 peptide to acquire selectivity to liver cancer cells via grp78

HIGHLIGHTS

  • who: Dina Mofed and collaborators from the Department of Microbial Genetics, Agricultural Genetic Engineering Research Institute (AGERl), ARC have published the article: Genetically Engineered Hepatitis C Virus-like Particles (HCV-LPs) Tagged with SP94 Peptide to Acquire Selectivity to Liver Cancer Cells via Grp78, in the Journal: (JOURNAL)
  • what: The authors propose a novel drug delivery system based on HCV-LPs with SP94 and RGD peptides mediated by a specific molecular chaperone (Grp78) associated with cancer drug resistance. Grp78 is one of the main reasons for drug resistance and the recurrence of the tumor; it . . .

     

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