Genetically predicted telomere length and alzheimer’s disease endophenotypes: a mendelian randomization study

HIGHLIGHTS

  • who: Blanca Rodru00edguez-Fernu00e1ndez from the CWellington, Barcelona, Spain have published the research: Genetically predicted telomere length and Alzheimeru2019s disease endophenotypes: a Mendelian randomization study, in the Journal: (JOURNAL)
  • what: The authors aimed to evaluate the potential causal role of TL in AD endophenotypes (i.e. cognitive performance N = 2233; brain age and AD-related signatures N = 1134; and cerebrospinal fluid biomarkers (CSF) of AD and neurodegeneration N = 304) through a Mendelian randomization (MR) analysis. For the purpose of the present study, APOE-u03b52/u03b54 individuals (N=47) were excluded. In this study, genetic associations . . .

     

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