Genetics and molecular biology

HIGHLIGHTS

  • who: Osteosarcoma and collaborators from the Wuhan Fourth Hospital, Department of Pulmonary and Critical Care Medicine, Wuhan, Hubei, China have published the paper: Genetics and Molecular Biology, in the Journal: (JOURNAL)
  • what: The authors show that niclosamide at sub-micromolar concentrations inhibits proliferation and migration and induces apoptosis in both parental and chemo-resistant cells with much less toxicity in normal osteoblastic cells. The work provides pre-clinical evidence that niclosamide can be repurposed for treating the findings also suggest the therapeutic value of to overcome chemo-resistance. The authors evaluated niclosamide as a potential . . .

     

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