HIGHLIGHTS
- who: William R. Reay from the (UNIVERSITY) have published the article: Genetics-informed precision treatment formulation in schizophrenia and bipolar disorder, in the Journal: (JOURNAL)
- what: There has already been utility in this approach demonstrated in psychiatry, such as atomoxetine that has been repurposed for attention deficit hyperactive disorder (ADHD ) and the anti-convulsant valproate for bipolar disorder . The authors propose a new implementation of the PES that is informed by genetically proxied mRNA or protein expression of drug_target genes. The authors investigated this novel approach in two highly heritable psychiatric disorders, schizophrenia (MIM: 181500 . . .
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