HIGHLIGHTS
- who: TALEN and collaborators from the Transfusion Medicine and Gene Therapy, Medical Center, University of Freiburg, Freiburg, Germany, Center for Chronic have published the research work: Genome Editing With TALEN, CRISPR-Cas9 and CRISPR-Cas12a in Combination With AAV6 Homology Donor Restores T Cell Function for XLP, in the Journal: (JOURNAL)
- what: The authors show that gene edited XLP patient T_cells have a restored, physiological level of SAP protein expression and restored SAPdependent immune functions equal to that of healthy controls in immunoassays of T:B signaling, restimulation-induced cell death (RICD) and cytotoxicity. The . . .
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