HIGHLIGHTS
- who: TYPE and collaborators from the University of Edinburgh, United Kingdom have published the paper: Genome organization in cardiomyocytes expressing mutated A-type lamins, in the Journal: (JOURNAL)
- what: In this review, the authors focused on the LADs organization and reorganization in cardiac disease context but other levels of three-dimensional genome organization can be disrupted in cardiac diseases (Meaburn et_al, 2007; Mewborn et_al, 2010; Rosa-Garrido et_al, 2017; Chapski et_al, 2021).
- how: These data showed that even a slightly change in chromatin organization in mutant cells can still participates to phenotype observed . . .
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