Genome-scale metabolic rewiring improves titers rates and yields of the non-native product indigoidine at scale

HIGHLIGHTS

• who: Deepanwita Banerjee from the Berkeley National Laboratory, Berkeley, CA, USAUniversity of have published the Article: Genome-scale metabolic rewiring improves titers rates and yields of the non-native product indigoidine at scale, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors examine if coupling production of a heterologous product to microbial growth is possible, and if such dependence could lead to high TRY and the ability to maintain production parameters across different growth modes and scales. This study implements genome scale MCS predictions via CRISPR interference that resulted in a strain where production . . .
  

   

  

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