Genome-wide analysis yields new loci associating with aortic valve stenosis

HIGHLIGHTS

  • who: Anna Helgadottir from the (UNIVERSITY) have published the article: Genome-wide analysis yields new loci associating with aortic valve stenosis, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors demonstrate that this new AS variant, rs17696696 in CFDP1, associates genome-wide significantly with CAD, like rs1830321 near TEX41 and the LPA rs10455872 (ref 6). The authors demonstrate that four CAD variants and one aortic root size variant associate with AS.
  • how: This variant was previously shown to associate with sick sinus syndrome and atrial fibrillation1011 and was recently reported also to . . .

     

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