Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis

HIGHLIGHTS

  • who: C. S. Gallagher from the (UNIVERSITY) have published the research: Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors report GWAS on both UL limited by HMB and solely on HMB, revealing potential targets for pharmacologic intervention: | https://doi.org/10.1038/s41467-019-12536-4 ARL14EP, ATM, TERT, and FGFR4.
  • how: Given shared risk loci and genetic correlation of UL and endometriosis the authors conducted an epidemiological meta-analysis including 402868 women from three population . . .

     

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