HIGHLIGHTS
- who: Sonia Shah from the (UNIVERSITY) have published the article: Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of March/25/2011
- what: The authors seek to relate HFassociated loci to putative effector genes through integrated analysis of expression data from disease-relevant tissues, including statistical colocalisation analysis. The authors evaluate the genetic evidence supporting a causal role for HF risk factors identified through observational studies using Mendelian randomisation and explore mediation of risk through conditional analysis. Using conditional analysis, the . . .
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