Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of alzheimer’s disease related proteins

HIGHLIGHTS

• who: Stephanie R. Oatman from the (UNIVERSITY) have published the paper: Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimeru2019s disease related proteins, in the Journal: (JOURNAL) of June/10,/2019
• what: Interestingly, although the authors focus on the AD pathology vs no pathology analyses, Mathys et_al also reported DE genes between early and late AD pathology in which the authors see upregulation of PRKD2 in neurons (fold change=0.51) in late AD. The authors report the identification of eight independent GWS loci that associate with brain levels of . . .
  

   

  

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