Genome-wide crispr screens identify gata6 as a proviral host factor for sars-cov-2 via modulation of ace2

HIGHLIGHTS

• who: Mau2019ayan Israeli from the Israel Institute have published the paper: Genome-wide CRISPR screens identify GATA6 as a proviral host factor for SARS-CoV-2 via modulation of ACE2, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The analysis showed that ACE2 expression decreases as early as 12 h post-GATA6-siRNA transfection (Fig 5f).
• how: For real-time PCR quantification of the virus a PFU calibration curve that was tested in parallel was utilized to express Ct values as calculated PFUs. Source data are provided with this paper.
• future . . .
  

   

  

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