Genome-wide identification of genes regulating dna methylation using genetic anchors for causal inference

HIGHLIGHTS

  • who: Paul J. Hop from the Department of Biomedical Data, Leiden University Medical have published the research: Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference, in the Journal: (JOURNAL)
  • what: The authors show that a substantial number of transcription factors affected DNA methylation at their experimentally determined binding sites. The authors report hundreds of genes that affect DNA methylation and provide key insights in the principles underlying epigenetic regulation. Experimental evidence for genes involved in the regulation of DNA methylation has been mainly obtained from in_vitro experiments focusing on . . .

     

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