HIGHLIGHTS
- who: Maysa Abu-Khalaf and collaborators from the Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University have published the article: Genomic Aberrations in Circulating Tumor DNAs from Palbociclib-Treated Metastatic Breast Cancer Patients Reveal a Novel Resistance Mechanism, in the Journal: (JOURNAL)
- what: The analyses in this study focused on functional mutations in exomes, including nonsynonymous SNV, frameshift/non-frameshift insertion and deletion, stop gain, and stop-loss variants. In the present study, although cfDNA samples obtained at the time of disease progression harbored more FBXW7 mutations than the corresponding baseline samples . . .
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