Genomic landscape and chronological reconstruction of driver events in multiple myeloma

HIGHLIGHTS

  • who: Francesco Maura from the Wellcome Sanger Institute University of of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy have published the Article: Genomic landscape and chronological reconstruction of driver events in multiple myeloma, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The study provides several novel insights into MM biology, taking advantage of WGS and serial sampling. The authors demonstrate here how hyperdiploidy reflects the sum of multiple and independent chromosomal gains over time, in contrast to prior hypotheses1-3.
  • how: The authors developed a composite analysis employing . . .

     

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