Genomic landscapes of canine splenic angiosarcoma (hemangiosarcoma) contain extensive heterogeneity within and between patients

HIGHLIGHTS

  • who: Shukmei Wong and collaborators from the Genome Sciences, Case Western Reserve University, Cleveland, Ohio, United States of America have published the paper: Genomic landscapes of canine splenic angiosarcoma (hemangiosarcoma) contain extensive heterogeneity within and between patients, in the Journal: PLOS ONE of 21/02/2022
  • what: This study has confirmed the presence of genomic variants and intratumoral heterogeneity in canine HSA that can facilitate hypothesis testing and methods development to meet these needs.
  • how: The authors identified significant intratumoral genomic regional heterogeneity via analysis of multiple sections from the same tumor.
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