Genotype specific pathogenicity of hepatitis e virus at the human maternal-fetal interface

HIGHLIGHTS

  • who: Jordi Gouilly from the CNRS III University, Toulouse, France have published the paper: Genotype specific pathogenicity of hepatitis E virus at the human maternal-fetal interface, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: Using an ex vivo model of first trimester maternal-fetal interface, the authors provide here the first evidence that the decidua and the placenta are prone to HEV-1 infection rather than HEV-3, resulting in the generation of infectious progeny virions.

SUMMARY

    Only a single study identified viral components in placental tissue from HEV-1 . . .

     

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