Ghrelin signaling in the cerebellar cortex enhances gabaergic transmission onto purkinje cells

HIGHLIGHTS

• who: Moritoshi Hirono from the DepartmentMedical University, u2011, Kimiidera, Wakayama, Wakayama, u20118509, Japan have published the paper: Ghrelin signaling in the cerebellar cortex enhances GABAergic transmission onto Purkinje cells, in the Journal: Scientific Reports Scientific Reports
• what: The authors examined spike train regularity of cerebellar neurons by measuring not only the coefficient of variation (CV) but also CV2, which detects variability less sensitive to changes in the mean firing u00adrate23. The study shows that ghrelin facilitates inhibitory GABAergic transmission at MLI-PC synapses by an increase in the frequency of spontaneous action potentials of MLIs . . .
  

   

  

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