Giardia duodenalis enolase is secreted as monomer during trophozoite-epithelial cell interactions, activates plasminogen and induces necroptotic damage

HIGHLIGHTS

  • who: Elisa Barroeta-Echegaray from the Medical Research Institute Mercedes Argentina Georgetown University, United States have published the Article: Giardia duodenalis enolase is secreted as monomer during trophozoite-epithelial cell interactions, activates plasminogen and induces necroptotic damage, in the Journal: (JOURNAL)
  • what: The authors tested this hypothesis and explored whether enolase contributes to Giardia's virulence.
  • how: The results were compared with the ones observed in control interactions assay in which no antibody was added. In the latter model similar results were obtained using H. sapiens enolase 1 (PDB ID 2psn) as template . . .

     

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