Gilteritinib enhances anti-tumor ef fi cacy of cdk4/6 inhibitor, abemaciclib in lung cancer cells

HIGHLIGHTS

  • who: CDK et al. from the College of Biological and Pharmaceutical Engineering, West Anhui University, Lu`an, China, Department of Physiology and have published the research work: Gilteritinib Enhances Anti-Tumor Ef fi cacy of CDK4/6 Inhibitor, Abemaciclib in Lung Cancer Cells, in the Journal: (JOURNAL)
  • what: The authors investigated the antitumor effect of abemaciclib alone, or in combination with gilteritinib in lung cancer cells, and demonstrated that gilteritinib enhances the cytotoxicity of abemaciclib in_vitro and in_vivo.
  • how: DESeq2 results were analyzed using a p and amplt 0.05 significance followed by . . .

     

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