Ginsenoside protopanaxadiol protects adult retinal pigment epithelial-19 cells from chloroquine by modulating autophagy and apoptosis

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  • who: Haesung Lee and colleagues from the Department of Bioactive Material Sciences and Research Center of Bioactive Materials, Jeonbuk National University, Jeonju, Jeollabuk-do, Republic of Korea have published the Article: Ginsenoside protopanaxadiol protects adult retinal pigment epithelial-19 cells from chloroquine by modulating autophagy and apoptosis, in the Journal: PLOS ONE of 13/07/2021
  • what: The authors investigated whether the relieves chloroquine-induced retinopathy by restoring lysosomotropic abnormalities in human pigment epithelial-19 cells. To achieve this, the authors focused on upstream and downstream autophagic and cell proliferation signals. Protopanaxadiol in CQ-induced . . .

     

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