Gitr/gitrl reverse signalling modulates the proliferation of hepatic progenitor cells by recruiting anxa2 to phosphorylate erk1/2 and akt

HIGHLIGHTS

• who: Yu He from the GITRL and GITR expression in human liver tissue The , primary liver hepatocellular carcinoma (LIHC) samples in The Cancer Genome Atlas (TCGA) clinical data, including RNA sequencing (RNA-seq) data and clinical data, were obtained using the R/Bioconductor package [52]Among the , LIHC samples, there were , HCC samples and , nontumour tissues. Two cases of non-HCC liver cancer were excluded, and , cases were excluded due to lack of GITRL expression. mRNA expression levels were normalised, and GITRL or GITR mRNA expression was compared between cancerous (N=342) and nontumour tissues (N=50 . . .
  

   

  

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