HIGHLIGHTS
- who: Maria Pechlivanidou and collaborators from the Medical School, University of, have published the article: Glial Gap Junction Pathology in the Spinal Cord of the 5xFAD Mouse Model of Early-Onset Alzheimeru2019s Disease, in the Journal: (JOURNAL)
- what: The aim of this study was to examine the alterations in astrocyte and related oligodendrocyte GJs in association with Au03b2 plaques in the spinal cord of the 5xFAD mouse model of AD. The authors propose an astrogliosis-driven shift in A/A GJ connectivity, implying an overactivation of Cx43 hemichannels and upregulated O/O GJ coupling supported . . .
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