Global characterization of extrachromosomal circular dnas in advanced high grade serous ovarian cancer

HIGHLIGHTS

• who: Yixuan Cen from the Clinical Specimens In this study, pairs of HGSOC primary and metastatic tissues (HGSOC, and HGSOC-M, ) were collected in , and subjected for Circle-Sequencing and transcriptome sequencingA panel of HGSOC tissues containing , primary tumor samples and , matched metastatic tumor samples were collected in , and used for validation by qRT-PCR analysis. The FFPE tissues of the same , HGSOC patients were also collected for validation by FISH assay and BaseScope assay. Tissue samples were immediately stored in liquid nitrogen after section and then transferred to , u00b0C until use. Another panel of FFPE tissues . . .
  

   

  

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