Global distribution of functionally important

HIGHLIGHTS

  • who: Yitian Zhou from the Division of Clinical Pharmacology, Department of Laboratory Medicine, Medical Diagnostics, Clinical Pharmacology, Karolinska University Germany have published the paper: Global distribution of functionally important, in the Journal: (JOURNAL)
  • what: The results revealed that CYP2C9 2 was most abundant in Europe and the Middle East whereas CYP2C9 3 was the main reason for reduced CYP2C9 activity across South Asia. This study provides a comprehensive map of the genetic and functional variability of CYP2C9 with high ethnogeographic resolution. The analysis showed that CYP2C9*2 is most prevalent in Middle Eastern populations (up . . .

     

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