Global trends and prospects about synaptic plasticity in alzheimer’s disease: a bibliometric analysis

SUMMARY

    As reported, the strength and efficiency of synaptic connections can be affected by the changes in the environment or the experience of the individuals (Krzeptowski et_al, 2018; MercerónMartínez et_al, 2021). The mechanisms of synaptic plasticity refer to not only its morphological modifications, such as the regeneration of axons and the formation of new synapse but also its molecular changes that alter the cellular response to neurotrasmitters (Mercerón-Martínez et_al, 2021). For instance, Aβ oligomers have been demonstrated to trigger astrogliosis and induce ROS generation in activated astrocytes (Wyssenbach et_al, 2016; Pereira Diniz et_al . . .

     

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