HIGHLIGHTS
- who: Jun Chen from the McGill University, Canada have published the research work: GLP-1 receptor agonist as a modulator of innate immunity, in the Journal: (JOURNAL)
- how: The results showed that Exendin-4 also promoted bone marrow-derived macrophage polarization to M2 phenotye and TGF-b1 secretion via PKASTAT3 signaling . Non-alcoholic fatty liver disease (NAFLD) induced by a high-fat diet was used to investigated the Kupffer cells M2 polarization in the liver which shows that liraglutide can reverse the negative effects of nonalcoholic fatty liver disease by modulating Kupffer cell M2 polarization . . .
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